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Bulletins

BIO - Biology

BIO 500 Biological Statistics

An introduction to biological statistics; emphasis on concepts of descriptive statistics and central tendency, inferential statistics, one-way ANOVA and correlation/linear regression. Prerequisites: Graduate standing or twelve (12) hours of biology. Recommended MTH 130.

Credits
3(2-2)

BIO 501 Evolution

Mechanisms of descent with modification are discussed in a framework of microevolution, speciation, and macroevolution. Prerequisites: BIO 212, 213 both with a C- or better; or BIO 326; or admission to the Biology M.S., Conservation Biology M.S., Biochemistry, Cell and Molecular Biology M.S., Biochemistry, Cell and Molecular Biology Ph.D. program, or Earth and Ecosystem Sciences Ph.D. program.

Credits
3(3-0)

BIO 502 Teaching Biology

Development of pedagogical content knowledge for teaching of secondary biology; required training course for prospective teachers of biology. Prerequisites: Completion of at least 22 credits of BIO coursework; GPA of at least 2.7 in BIO classes; Tier Two - Admission of Candidacy to Teacher Education.

Credits
3(2-3)

BIO 509 Ichthyology

Anatomy, taxonomy, physiology, natural history, and ecology of fishes with laboratory emphasis on fishes of the Great lakes region. Prerequisites: BIO 212, 213 both with a grade of C- or better; or BIO 218; or graduate standing.

Credits
4(3-3)

BIO 510 Fisheries Biology and Management

Analysis of fish populations, management of fisheries resources, and other problems related to freshwater fisheries. Prerequisites: BIO 212, 213 both with a C- or better; or admission to the Biology M.S., Conservation Biology M.S., or Earth and Ecosystem Sciences Ph.D. program.

Credits
4(3-3)

BIO 511 Aquatic Insects

Natural history and systematic of freshwater insects. Prerequisites: BIO 218 or graduate standing.

Credits
3(1-4)

BIO 515 Ornithology

An introduction to avian biology emphasizing evolution, systematics, and the annual cycle. Identification, song, and general ecology are studied through field trips and laboratory work. Prerequisites: BIO 212, 213 both with a grade of C- or better; or BIO 218; or graduate standing.

Credits
4(2-4)

BIO 518 Animal Behavior

Behavior in invertebrate and vertebrate organisms related to genetics, morphology, and the ecology of animal populations. Prerequisites: BIO 218 or graduate standing.

Credits
3(2-3)

BIO 519 Invertebrate Diversity

An advanced review of the evolution and ecology of invertebrates emphasizing the identification, collection, and conservation of aquatic macroinvertebrates in the Great Lakes region. Prerequisites: BIO 212, 213 both with a C- or better; or BIO 218; or admission to the Biology M.S., Conservation Biology M.S., or Earth and Ecosystem Sciences Ph.D. program.

Credits
4(2-4)

BIO 520 Great Lakes Mollusks

An examination of the ecology, life history, taxonomy, evolution, and conservation status of freshwater mollusks (bivalves and gastropods) from the Great Lakes region. Prerequisites: BIO 212, 213 both with a grade of C- or better; or BIO 218; or graduate standing.

Credits
2(1-3)

BIO 523 Ecology and Systematics of Freshwater Algae

Examination of the systematics and ecology of freshwater algae using a systems approach to identify native assemblages in wetlands, streams, lakes, and the Great Lakes. Prerequisites: BIO 212, 213 both with a C- or better; or BIO 218; or admission to the Biology M.S., Conservation Biology M.S., or Earth and Ecosystem Sciences Ph.D. program.

Credits
3(2-3)

BIO 524 Molecular Biology

Molecular nature of genes and recombinant DNA techniques, explored through the analysis of experimental data. Prerequisites: BIO 326, CHM 346; or graduate standing. Recommended: CHM 521, 522.

Credits
3(3-0)

BIO 525 Plant Ecology

A study of plants emphasizing physical and biotic interrelationships, and factors which govern their distribution. Field work stressed. Prerequisites: BIO 340; a plant identification course highly recommended.

Credits
4(2-4)

BIO 526 Limnology

Physical, chemical, and biological properties of inland aquatic ecosystems focusing on lakes. Topics include basin origin, light, mixing, organism diversity, nutrient cycling, and food webs. Prerequisites: BIO 212, 213 both with a C- or better; or BIO 340; or graduate standing. Recommended: One of: CHM 120, 132, 161.

Credits
3(3-0)

BIO 527 Limnological Methods

A quantitative examination of the physical, chemical and biological aspects of lake ecosystems. Pre/Co-Requisite: BIO 526.

Credits
2(0-4)

BIO 534 Endocrinology

Endocrine system function including major endocrine glands, hormone synthesis, mechanisms of hormone action, and regulation of key body functions. Prerequisites: BIO 212, 213, 392 all with a grade of C- or better; or graduate standing.

Credits
3(3-0)

BIO 536 Histology

Study of cells and tissues that comprise human organ systems with emphasis on their integration and function using light microscopy. Prerequisites: BIO 212, 213 both with a C- or better; or BIO 390 or 392; or admission to the Biology M.S., Biochemistry, Cell and Molecular Biology M.S., Biochemistry, Cell and Molecular Biology Ph.D. program, or Earth and Ecosystem Sciences Ph.D. program.

Credits
3(2-3)

BIO 537 Immunology

A description of the biological and biochemical mechanisms of the immune response. Emphasis will be placed on adaptive immunity activation, immunobiology, and immune system dysfunction. Prerequisites: BIO 212, 213 both with a C- or better and one of: BIO 320, 324, 392; or BIO 211 with a C- or better, BIO 392, and a signed major in biochemistry or neuroscience; or admission to the Biology M.S., Chemistry M.S., Biochemistry, Cell and Molecular Biology M.S., or Biochemistry, Cell and Molecular Biology Ph.D. program. Recommended: CHM 425 or 521.

Credits
3(3-0)

BIO 539 Virology

Basic principles of viral structure and replication. Provides a detailed survey of viruses, including emergent viral pathogens. Explores viral evolution, anti-viral drugs and vaccines. Prerequisites: BIO 324, 326 or Graduate Status in the Biology Department.

Credits
3(3-0)

BIO 540 Mammalogy

Survey of evolution, taxonomy, behavioral ecology, physiological ecology, conservation biology, and management as these relate to Class Mammalia. Prerequisites: BIO 212, 213 both with a grade of C- or better; or BIO 218; or graduate standing.

Credits
4(3-3)

BIO 541 Wildlife Biology and Management

Presents the basic ecological principles and the varied techniques utilized in managing the wildlife resource. Prerequisites: BIO 212, 213 both with a grade of C- or better; or BIO 340; or graduate standing.

Credits
4(2-4)

BIO 544 Developmental Biology

Patterns and cellular/molecular mechanisms of embryonic development, emphasizing animals. Prerequisites: BIO 212, 213 with a grade of C- or better; or BIO 324, 326; CHM 132 or 161.

Credits
4(3-3)

BIO 545 Molecular Genetics

Genetic approach to fundamental biological problems. Covers genetic techniques and modern molecular methods, including recombinant DNA technology and functional genomics in model systems and humans. May be offered as Writing Intensive. Prerequisites: BIO 212, 213 both with a C- or better; or BIO 211 with a C- or better and a signed major in Biochemistry or Neurosciences; or BIO 326; CHM 342 or 346; or graduate standing.

Credits
3(3-0)

BIO 546 Molecular Genetics Laboratory

Laboratory course, to accompany BIO 545, explores genetic techniques and modern molecular methods, including recombinant DNA technology and functional genomics in model systems. Pre/Co-requisites: BIO 545.

Credits
1(0-3)

BIO 549 Herpetology

Survey of extant amphibians and reptiles from standpoint of morphology, behavior, physiology, evolution, and ecology. Local collecting field trips required. Prerequisites: BIO 218 or graduate standing.

Credits
3(2-3)

BIO 550 Transmission Electron Microscopy

Biological specimen preparation and examination using transmission electron microscopy. Use of digital photography in electron micrograph production. Prerequisites: BIO 212, 213 both with a grade of C- or better; or BIO 324; BIO 330; or graduate standing; permission of instructor.

Credits
4(1-6)

BIO 552 Scanning Electron Microscope Technique

Principles and techniques of SEM including biological specimen preparation and examination. Use of digital photography in electron micrograph production. Prerequisites: BIO 212, 213 both with a grade of C- or better, or BIO 324; BIO 330; or graduate standing.

Credits
4(3-3)

BIO 553 Confocal Microscopy

Principles and practice of biological confocal laser scanning microscopy, including sample preparation and the use of molecular probes. Prerequisites: BIO 212, 213 both with a grade of C- or better; or BIO 324; BIO 330; or graduate standing.

Credits
3(2-3)

BIO 555 Great Lakes Wetland and Aquatic Plants

The biology of wetland plants including: identification, systematics, and ecology. Students will visit wetlands throughout Michigan and learn to identify common wetland and aquatic plants. Prerequisites: BIO 203 or graduate standing.

Credits
4(2-4)

BIO 557 Woody Plants of Michigan

The biology of woody plants including their identification, anatomy and physiology, systematics, ecology and evolution. Students will learn Michigan native trees and shrubs. Prerequisites: BIO 203; or BIO 212, 213 with a grade of C- or better; or graduate standing.

Credits
4(2-4)

BIO 559 Field Botany

The collection, identification, and preparation of herbarium specimens from the local flora. Prerequisites: BIO 203.

Credits
3(2-3)

BIO 560 Avian Ecology

The behavior, community organization, and ecological relationships of birds are examined through discussion of current literature, investigative field work, and other techniques. May be offered as Writing Intensive. Prerequisites: BIO 212, 213 both with a C- or better; or graduate standing. Recommended: BIO 515.

Credits
3(2-3)

BIO 561 Wetland Ecology and Management

The study of wetland ecosystem structure and function. Chemical, physical, and biological processes will be put into the context of conservation, management, and restoration. Prerequisite: BIO 340.

Credits
3(3-0)

BIO 562 Plant Systematics and Evolution

In-depth study, covering important topics in plant identification, evolution and systematics. Prerequisites: BIO 203 or graduate standing.

Credits
4(3-3)

BIO 565 Microbial Diversity and Physiology

This course explores the diversity of microorganisms, including methods for classifying microorganisms and assessing their diversity, and a detailed survey of microbial metabolic diversity. Prerequisite: BIO 326 or Biology graduate status.

Credits
3(3-0)

BIO 566 Microbial Diversity and Physiology Laboratory

This is an advanced laboratory course that explores experimental techniques used to study the diversity and physiology of microorganisms. This laboratory course accompanies BIO 565. Prerequisite: BIO 326 or Biology graduate status. Co-requisite: BIO 565.

Credits
1(0-3)

BIO 567WI Biogeochemistry

Examines the molecular mechanisms by which microorganisms drive the cycling of Earth’s major elements. Prerequisites: BIO 212, 213 both with a grade of C- or better; or BIO 208; CHM 132; or graduate standing in a CST program.

Credits
3(3-0)

BIO 570 Cellular Dynamics

A course that explores advanced topics in cell biology focusing on landmark discoveries and experimental techniques using the primary literature. Prerequisites: BIO 324, 326; or Biology graduate status.

Credits
3(3-0)

BIO 571 Cellular Dynamics Laboratory

An advanced laboratory course that explores experimental techniques in cell biology research. This is a laboratory course that accompanies BIO 570. Prerequisites: BIO 324, 326; or Biology graduate status. Co- requisite: BIO 570.

Credits
1(0-3)

BIO 575 Applied Bioinformatics

Application of bioinformatics techniques. Topics include: gene finding, pairwise and multiple sequence alignments of DNA and protein sequences, and the use of GenBank and BLAST. Prerequisites: BIO 212, 213 with a C- or better; or graduate standing in a Master’s or Ph. D. program in the College of Science and Engineering.

Credits
4(3-3)

BIO 576 Mammalian Cell Culture

Practical aspects of mammalian cell culture, aseptic technique, cell maintenance, differentiation, and cryopreservation. Prerequisites: BIO 212, 213 both with a C- or better; or graduate standing.

Credits
3(1-5)

BIO 576WI Mammalian Cell Culture

Practical aspects of mammalian cell culture, aseptic technique, cell maintenance, differentiation, and cryopreservation. Writing Intensive. Prerequisites: BIO 212, 213 both with a C- or better; or graduate standing.

Credits
3(1-5)

BIO 580 Medical Microbiology

Focuses on the relationships between humans and pathogenic microbes. Covers major groups of medically important microorganisms, pathological consequences of infection, diagnosis, and clinical case problemsolving. Prerequisites: BIO 320, 392 both with a C+ or better; or BIO 208, 211, one of: BIO 392 or HSC 215 all with a C+ or better, and a signed major in Neuroscience or Biochemistry; or graduate standing.

Credits
4(2-4)

BIO 585 Conservation Medicine

Examines various diseases and their importance to wildlife, domestic animals, and humans. Epidemiology and ecology of diseases are discussed within the framework of conservation medicine. Prerequisites: BIO 208, 340; or graduate standing .

Credits
3(3-0)

BIO 590 Cardiovascular Physiology

Basic principles of normal mammalian cardiovascular physiology. Prerequisites: BIO 392 or graduate standing.

Credits
3(3-0)

BIO 591 Neurophysiology

Principles of nervous system function: cytology, electrophysiology, ion channels, membrane potentials, neurochemistry, synaptic function and its modification, sensory physiology. Prerequisites: BIO 392.

Credits
3(3-0)

BIO 595 Cancer Biology

Examination of the underlying molecular, cellular, and genetic pathways involved in carcinogenesis, tumor growth, angiogenesis, and metastasis. Additional topics include tumor immunology and treatment strategies. Prerequisites: BIO 212, 213 both with a grade of C- or better; or BIO 324, 326; CHM 342 or 345; or graduate standing. Recommended: CHM 425 or 521.

Credits
3(3-0)

BIO 597 Special Topics in Biology

Topics of special interest that are not normally included in existing courses. Specific topics and instructor’s prerequisites will be announced in Course Search and Registration. Prerequisites: BIO 212, 213 both with a grade of C- or better; completion of 56 semester hours; or graduate standing; additional instructor prerequisites will be announced in the Course Search and Registration.

Credits
1-9(Spec)

BIO 600 Biological Research Design and Analysis

An examination of the proper research design and statistical analysis needed to solve problems in laboratory and field biology. Recommended: BIO 500.

Credits
3(2-2)

BIO 610 Biology Colloquium

Advanced study of selected subject areas through lecture and/or similar colloquia. Prerequisite: Graduate status.

Credits
1-9(Spec)

BIO 619 Continuing Registration for Final Research Project

A non-credit course intended for students who have completed all program credits but still need to use university resources to complete their degree requirements.

Credits
1(1-0)

BIO 620 Biology Practicum

Practical experience in methodology and techniques in selected field or laboratory-oriented topics. Prerequisite: Admission to the Biology or EES graduate program.

Credits
1-9(Spec)

BIO 626 Topics in Genetics

Various advanced topics in genetics ranging from transmission genetics to molecular genetics and evolution. Student participation is expected. May be repeated for a maximum of 3 hours. Prerequisite: Admission to the Biology M.S., Conservation Biology M.S., Biochemistry, Cell and Molecular Biology M.S., Biochemistry, Cell and Molecular Biology Ph.D. program, or Earth and Ecosystem Sciences Ph.D. program.

Credits
1-3(Spec)

BIO 629 Topics in Eukaryotic Molecular Genetics

Seminar on current research papers in molecular genetics of animals, plants and fungi. Student presentations and discussions expected. May be repeated up to 4 credits. Prerequisites: Graduate standing in the Biology M.S. program.

Credits
1-4(Spec)

BIO 630 Art of Scientific Communication

Training in and practice of professional scientific communication, including peer-reviewed scientific papers, grant proposals, posters, and oral presentations for scientific conferences. Discussion of professional development. CR/NC only.

Credits
3(2-1)

BIO 635 Toxicology

Study of toxic chemicals, their effects on living organisms, and the metabolism and fate of the chemical in the organism. Prerequisites: BIO 392, CHM 346, CHM 521, CHM 522.

Credits
3(3-0)

BIO 637 Topics in Immunology

Advanced coverage of various topics in immunology. May be repeated as offered to a maximum of 3 credit hours. Prerequisite: BIO 537.

Credits
1-3(Spec)

BIO 642 Advanced Statistical Methods for Research

Examines the assumptions and utility of statistical techniques used in research, with emphasis on applications in biology and multivariate techniques with complex datasets. Prerequisite: BIO 500.

Credits
3(3-0)

BIO 650 Population and Community Ecology

Theoretical and empirical considerations of mechanisms affecting the dynamics of and interactions between populations in nature. Prerequisites: Graduate status inBiology or Earth and Ecosystem Science.

Credits
4(3-2)

BIO 651 Topics in Ethology

Seminar on current research papers in animal behavior. May be repeated up to 4 credits.

Credits
1-4(Spec)

BIO 652 Behavioral Ecology

An integration of behavior and ecology from the standpoint of species diversity, habitat utilization, reproduction, and competition. Field observations illustrating adaptation and behavior. Prerequisite: Admission to the Biology M.S., Conservation Biology M.S., Biochemistry, Cell and Molecular Biology M.S., Biochemistry, Cell and Molecular Biology Ph.D. program, or Earth and Ecosystem Sciences Ph.D. program.

Credits
3(2-3)

BIO 653 Stream Ecology

Structure and function of stream ecosystems with emphasis on biological processes. Prerequisites: BIO 340 or admission to Biology MS Program.

Credits
3(2-3)

BIO 656 Fish Ecology

A study of the ecological relationships of fishes.

Credits
2(2-0)

BIO 657 Fisheries Management

A study of specific habitats as related to fisheries management, habitat alteration problems, alternative management solutions, special techniques, and specific management topics. Prerequisites: Graduate status.

Credits
2(2-0)

BIO 658 Zooplankton Biology

An examination of the taxonomy, physiology, behavior and ecology of planktonic animals. Prerequisites: BIO 218, 340.

Credits
3(2-3)

BIO 680 Conservation Biology

Addresses dynamics and problems of perturbed species, communities, and ecosystems and practical aspects of implementing protection. Recommended: BIO 500.

Credits
3(3-0)

BIO 685 Phylogenetics

Detailed study of phylogeny reconstruction, comparative evolutionary methods, and how to critically evaluate evolutionary studies. Prerequisite: Graduate standing in Biology or Earth and Ecosystems Science. Recommended: Prior coursework in plant biology, zoology, microbiology and genetics.

Credits
3(3-0)

BIO 690 Conservation Genetics

Students learn technical and theoretical genetic methods used in conservation while generating, analyzing, and interpreting data to generate sound scientific conclusions. Prerequisite: Admission to the Biology M.S., Conservation Biology M.S., Biochemistry, Cell and Molecular Biology M.S., Biochemistry, Cell and Molecular Biology Ph.D. program, or Earth and Ecosystem Sciences Ph.D. program.

Credits
4(3-3)

BIO 691 Landscape Ecology

Students gain a technical and theoretical foundation of landscape ecology as it applies to conservation biology and discuss applications of landscape ecology and GIS tools. Pre/Co-requisite: BIO 680. Recommended: BIO 500 or STA 382; GEO 203, 303.

Credits
4(3-3)

BIO 692 Topics in Physiology

Seminars, technique courses or lecture courses on new frontiers in physiology or of special interest. May be repeated for a maximum of 4 hours. Prerequisites: BIO 392.

Credits
1-4(Spec)

BIO 695 Graduate Internship in Biology

An in-depth work experience in the graduate student’s research area performed under the supervision of a trained professional in the selected area of biology. Prerequisite: A graduate internship agreement must be signed and on file in the Biology office or with the Director of the Biological Station at least four weeks prior to enrollment.

Credits
1-6(Spec)

BIO 730 Seminar

Formal, oral departmental presentation of Plan A thesis research. Required of students receiving the M.S. in Biology or Conservation Biology, Plan A. CR/NC only. Prerequisite: Permission of thesis committee Chair.

Credits
1(1-0)

BIO 790 Research in Biology

Research experience in the laboratory and/or the field. CR/NC only.

Credits
2-4(Spec)

BIO 798 Thesis

Research resulting in written thesis. CR/NC only. Prerequisite: Plan A thesis prospectus on file in the Biology Department office.

Credits
1-9(Spec)